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Tadalafil Femalefil is marketed as a treatment for sexual dysfunction in women, although its effectiveness and safety are not as well established as those of similar medications for men. The active ingredient in Tadalafil Femalefil is tadalafil, which is a phosphodiesterase type 5 (PDE5) inhibitor. In men, tadalafil works by increasing blood flow to the penis, but its use in women is less clearly defined. Some studies suggest it might improve sexual function in women with certain conditions, but research is still limited and ongoing.